Botox for Overactive Bladder and Urge Incontinence

When Bladder Urgency Does Not Respond to Medication

Botox injections for overactive bladder in Central Wyoming for adults with urge incontinence uncontrolled by prior treatment

Overactive bladder and urge urinary incontinence can persist even after a patient has tried medications, behavioral modification, and pelvic floor therapy. Central Wyoming Urological Associates, PC offers Botox (onabotulinumtoxinA) injections as an in-office treatment for adults whose urgency and leakage have not been adequately controlled through those earlier steps. The procedure targets the bladder muscle directly and is distinct from treatments for stress incontinence — the leakage that occurs with coughing, sneezing, or lifting.


Botox works by relaxing the bladder wall and reducing the involuntary muscle contractions that generate the sudden, strong urge to urinate and cause leakage before a patient can reach the restroom. The injection is placed into the bladder muscle at several points using a thin scope, called a cystoscope, passed into the bladder after a local anesthetic is applied. No incisions are made, no general anesthesia is required, and patients return home the same day. The injection portion of the procedure typically takes only a few minutes.


To discuss whether Botox injections are appropriate for your bladder condition, schedule a consultation with Central Wyoming Urological Associates, PC.

Person holding lower abdomen with red pain highlight over pelvic area

How the Procedure Works and What Patients Notice Afterward

During the procedure, the bladder is first numbed with a local anesthetic to limit discomfort. The urologist then passes the cystoscope into the bladder and injects small, precisely placed amounts of onabotulinumtoxinA into the bladder muscle at multiple sites. Because the medication is delivered directly into the muscle tissue rather than taken systemically, it acts at the source of the involuntary contractions rather than through the bloodstream. Patients sit or lie on the procedure table throughout and are not sedated.


Many patients notice a reduction in urgency and leakage episodes within a few days of the injection. Clinical studies report that the full effect is typically seen within one to two weeks. In those studies, roughly 70 to 80 percent of patients experienced a meaningful reduction in leakage episodes, urgency frequency, and nighttime waking — though individual results vary and these figures reflect study populations, not a promise of what any individual patient will experience. After the procedure, patients can usually observe fewer urgent episodes, longer intervals between bathroom visits, and fewer nighttime awakenings.


Botox for overactive bladder is a maintenance treatment rather than a permanent solution. Studies show the effect generally lasts six to twelve months, with many patients falling in the six-to-nine-month range. Repeat injections are needed when symptoms return, and planning for that schedule is part of ongoing management discussions with your urologist. For patients interested in a longer-term option, sacral neuromodulation with InterStim is also offered by Central Wyoming Urological Associates, PC and may be worth discussing at your consultation.

Questions About How This Treatment Is Performed

The following questions address how Botox injections for overactive bladder are carried out, what to expect before and after the procedure, and how the treatment differs from other options. If your question is not covered here, a consultation is the right place to work through the specifics of your situation.


  • What types of incontinence does this treatment address, and what does it not treat? Botox injections treat urge urinary incontinence — leakage triggered by a sudden, strong urge to urinate — and the urgency and frequency associated with overactive bladder. The treatment does not address stress urinary incontinence, which is the leakage that occurs with physical activity, coughing, sneezing, or lifting.
  • How is the cystoscope procedure performed and how long does it take? After the bladder is numbed with a local anesthetic, a thin flexible or rigid scope is passed through the urethra into the bladder, and the urologist injects onabotulinumtoxinA into the bladder muscle at multiple sites using a fine needle passed through the scope. The injection portion typically takes only a few minutes, though the full appointment is longer to allow for preparation and post-procedure observation.
  • What are the most common side effects following the injection? The most frequently reported side effects are urinary tract infection and temporary mild burning or a small amount of blood in the urine in the days after the procedure. Approximately six percent of patients in clinical studies experienced difficulty fully emptying the bladder and needed to perform intermittent self-catheterization for a period until the effect diminished. Your urologist will review the complete list of potential risks before proceeding.
  • When should a patient consider repeating the injection? Because the effect of Botox on the bladder muscle is temporary, most patients require repeat injections when symptoms return — typically somewhere between six and twelve months after the prior treatment. Your urologist will monitor how you respond and discuss timing based on when your symptoms begin to increase again.
  • How does a urologist determine whether a patient is a candidate for this procedure? Candidacy is generally evaluated based on the type of incontinence present, the documented response to prior treatments such as anticholinergic or beta-3 medications and behavioral therapy, and the patient's overall health and ability to self-catheterize if needed. Patients in Central Wyoming who have tried and not responded adequately to first-line treatments are typically the population for whom this procedure is considered.


Central Wyoming Urological Associates, PC evaluates each patient individually to determine whether Botox injections are the appropriate next step given their history, bladder function, and treatment goals. To review your options and ask questions specific to your situation, contact the office to arrange a consultation.